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Pregabalin may cause dizziness, somnolence and other symptoms and signs of central nervous system depression. Accordingly, the advice is neither to drive a car nor to operate other complex machinery until sufficient experience has been gained on MEBAAL Plus to gauge whether or not it affects the mental and/or motor performance adversely. If vision disturbances occur during Pregabalin therapy, medical advice must be sought. Also unexplained muscle pain, tenderness, or weakness, especially accompanied by malaise or fever requires prompt medical attention.
MEBAAL Plus must be advocated with caution in heart failure and diabetic patients in view of possibility of edema and weight gain induced by Pregabalin. Diabetic patients taking Pregabalin may develop skin ulcerations. MEBAAL Plus must be advocated with due precaution in renal dysfunction.
MEBAAL Plus must be advocated with caution along with thiazolidinediones in view of weight gain and fluid retention possibility with both these agents. It is not to be taken along with alcohol, or be combined with other central nervous depressants.
Antiepileptic drugs such as MEBAAL Plus should not be abruptly discontinued because of the possibility of increasing seizure frequency; rapid discontinuation may result in insomnia, nausea, headache, or diarrhea. MEBAAL Plus is not intended solely for treatment of anemias or providing vitamin A, for those nutritionally deficient in it.
MEBAAL Plus, like any other anti-epileptic drug must not be discontinued abruptly due to the possibility of increasing seizure frequency; rapid discontinuation may also, result in insomnia, nausea, headache, or diarrhea. If MEBAAL Plus is to be stopped, it must be done gradually over 1 week. It has been demonstrated, but not conclusively, that intake of Pregabalin could cause new, or worsening of preexisting tremors.
Since Pregabalin can cause dizziness, somnolence and other manifestations of central nervous system depression, patients should be advised neither to drive nor to operate complex machinery until they have gained sufficient experience on MEBAAL Plus to gauge whether or not it affects their mental and/or motor performance adversely.
If vision disturbances occur during Pregabalin therapy, medical advice must be sought. Also unexplained muscle pain, tenderness, or weakness, especially accompanied by malaise or fever requires prompt medical attention.
MEBAAL Plus must be advocated with caution along with thiazolidinediones in view of weight gain and fluid retention possibility with both these agents. It is not to be taken along with alcohol, or be combined with other central nervous depressants.
